Home Blood Test Guide

Blood test subscription: what you get, what it costs, and the catches

A blood test subscription bills you on a schedule for repeat lab panels, and in 2026 the main options cost $298 to $1,788 a year depending on how often you test. Here is how the models compare, what each costs over 12 months, and the renewal rules to check before you sign up.

SiPhox Health membership
SiPhox Health membership
From $124 + $25 shipping per test

Best blood test subscription if you want to retest every 1, 3 or 6 months at home without a needle, and switch between four 14 to 31 marker panels each time.

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Quick answer

A blood test subscription (also sold as a blood test membership) is a plan that charges you on a schedule and sends you, or books you, a repeat lab panel each time. In 2026 there are three models. Per-test cadence: SiPhox charges $149 per test all-in and you choose monthly, quarterly or every six months, which works out at $298 to $1,788 a year. Yearly membership: Function Health ($365) and Superpower ($349) include two venous lab draws and 150 to 160+ tests a year. Monthly per-test: Rythm Health charges $79 a test before shipping.

$149SiPhox per test, with shipping
$596SiPhox quarterly, 12 months
$365Function Health, 12 months
$349Superpower, 12 months

If you want to test more than twice a year without a needle or a lab visit, the best at home blood test subscription for most people is SiPhox on a quarterly cadence at $596 a year. If you only want the biggest possible panel once or twice a year and do not mind a Quest draw, Function or Superpower give more markers per dollar.

Retest at home every 1, 3 or 6 monthsSiPhox Longevity Essentials: 31 biomarkers per test from an upper-arm draw, $124 plus $25 shipping, switch panels any cycle.
See SiPhox plans

What a subscription gets you vs one-off tests

You do not need a subscription to get blood work without a doctor. Labcorp OnDemand sells a Comprehensive Health Test (CMP, CBC, lipids, HbA1c and urinalysis) for $189, and SiPhox sells each core panel as a one-off kit for $149. A subscription earns its place when you want the same markers measured repeatedly, because one result is a snapshot. The American Urological Association, for example, says low testosterone should only be diagnosed after two early morning measurements on separate days.

One-off test Subscription
Price per test $149 (SiPhox kit) to $189 (Labcorp Comprehensive) $149 per SiPhox test; about $175 to $183 per draw on Function or Superpower
Trend tracking You compare PDFs yourself Results plotted over time in one dashboard
Commitment None Renews until you cancel
Best for A single baseline, or checking one marker Watching a number respond to a change

The catch is the obvious one: a subscription keeps charging after your motivation fades. We cover the renewal rules below.

The three blood test subscription models

1. Per-test cadence (SiPhox Health)

You pay per testing cycle, not per year. SiPhox charges $124 plus $25 US shipping per test and advertises $99 plus shipping for a new member's first test. You pick monthly, quarterly or every six months, and each cycle you can switch between four included panels: Longevity Essentials (31 markers), Heart & Metabolic (28), Thyroid Focus (21) and Hormone Focus (14). Ultimate 360 (62 markers) costs $125 more per test. Collection is at home with the needle-free EasyDraw arm device. Our SiPhox review covers the whole service and SiPhox cost works through every price.

2. Yearly membership with lab draws (Function Health, Superpower)

One annual fee covers two venous draws at a Quest lab, an initial panel and a retest. Function Health is $365 a year for 160+ lab tests and includes clinician notes on results. Superpower is $349 a year for 150+ markers and says you can cancel any time, with the membership staying active to the end of the paid year. At-home draws cost extra on both. See our Function Health review and Function Health vs Superpower.

3. Monthly per-test plans (Rythm Health, and InsideTracker's hybrid)

Rythm Health charges $79 a test on a monthly plan (first test $59.25), measures 25+ markers from an upper-arm device, and lets you skip up to 90 days or cancel without fees. It quotes results within 48 hours once the lab has the sample. InsideTracker is a hybrid: a $149 yearly membership that renews at full price, plus paid blood tests; its Ultimate plan is $489 for the membership and one test. Details in our Rythm Health review and InsideTracker review.

Yearly cost of each blood test subscription

Prices below were read from each company's site on September 29, 2026 and include SiPhox's $25 shipping per test. Marker counts are per test for SiPhox and Rythm, and per year for the lab-draw memberships.

Plan Tests a year Markers Cost for 12 months Needle?
SiPhox, every 6 months 2 31 per test $298 No
SiPhox, quarterly 4 31 per test $596 ($571 with the $99 first test) No
SiPhox, quarterly with one Ultimate 360 4 31, 31, 31 and 62 $721 No
SiPhox, monthly 12 31 per test $1,788 No
Function Health 2 draws 160+ a year $365 Yes, Quest draw
Superpower 2 draws 150+ a year $349 Yes, Quest draw
Rythm Health, monthly 12 25+ per test $948 before shipping No
InsideTracker Ultimate 1 up to about 48 $489 Yes, Quest draw
Everlywell 360 1 83 $399 Yes, Quest draw

Two things the table hides. First, SiPhox's prepay options and intro offers change the first year, so check the current SiPhox offers. Second, Function and Superpower cost more in New York and New Jersey, and SiPhox does not serve New York or Hawaii at all.

What 12 months of each subscription costs
SiPhox, every 6 months$298Superpower$349Function Health$365Everlywell 360$399InsideTracker Ultimate$489SiPhox, quarterly$596SiPhox, quarterly + 1 Ultimate 360$721Rythm Health, monthly$948SiPhox, monthly$1,788

Our arithmetic from list prices checked 29 Sep 2026. SiPhox includes $25 shipping per test at the $149 list price (the $99 first-test offer takes $25 off year one). Rythm is $79 x 12 before shipping.

The chart makes the trade-off plain: the two lab-draw memberships sit at the cheap end because they include only two draws, while SiPhox's cost scales with how often you test. At two tests a year SiPhox is the cheapest plan on the list; at twelve it is the most expensive.

Cost per biomarker result

Divide the yearly cost by the number of marker results you get back and the picture flips. Function Health works out at about $2.28 per test result and Superpower about $2.33. SiPhox quarterly on Longevity Essentials gives 124 results for $596, or about $4.81 each. Rythm is about $3.70 a marker if you pay about $100 all-in per test for its 27-marker men's panel.

Cost per biomarker result over a year
Function Health$2.28Superpower$2.33Rythm Health$3.7SiPhox Ultimate 360$4.42SiPhox Longevity, quarterly$4.81Everlywell 360$4.81InsideTracker Ultimate$10.19

Our arithmetic: yearly or per-test price checked 29 Sep 2026 divided by marker results (Function 160+, Superpower 150+, Rythm 27, Ultimate 360 62, Longevity 4 x 31, Everlywell 83, InsideTracker 48). With the $99 first test, SiPhox quarterly is $4.60 in year one.

That does not make the lab-draw memberships better for everyone. Marker counts include calculated ratios on SiPhox, and "160 tests" on Function includes markers most people will never act on. What matters is the cost of the markers you want, as often as you want them. Our blood test cost calculator does that math for your own list, and the at-home blood test cost guide compares one-off prices.

Panel Biomarkers per test Upgrade cost Per test, with shipping Cost per biomarker
Longevity Essentials 31 Included $149 $4.81
Heart & Metabolic 28 Included $149 $5.32
Thyroid Focus 21 Included $149 $7.10
Hormone Focus 14 Included $149 $10.64
Ultimate 360 62 +$125 $274 $4.42
GLP Optimization 46 +$75 $224 $4.87

Cancellation and auto-renew catches

Billing complaints are a normal part of subscription health services. In the 20 most recent one-star Trustpilot reviews of SiPhox we read, 6 were billing or renewal disputes. Most are avoidable if you know the rules before you join.

  • SiPhox renews on your cadence until you cancel. Its terms say the subscription renews automatically and indefinitely. You can change the cadence or cancel from your account portal. There is no refund for a period once that period's kit has shipped, so cancel before the ship date. If you prepaid for a year, cancelling stops the renewal at the end of that period.
  • Intro prices end. SiPhox's $99 first test renews at $124 plus $25 shipping. Rythm's $59.25 first test becomes $79.
  • Shipping is extra. SiPhox charges $25 per test in the US and $50 to Canada, on every renewal.
  • InsideTracker's membership renews yearly at $149, with an email reminder two weeks before.
  • Superpower lets you cancel any time with no fee, and your membership runs to the end of the paid year.
  • Unused kits still count. A kit that sits in a drawer was still paid for. If you are not using them, move to a six-month cadence rather than let kits pile up.
Simple habit

When you join any blood test membership, put the next renewal date in your calendar with a reminder three days before. That one step prevents most of the complaints we read.

Who benefits from frequent testing

Most healthy adults with normal results do not need blood work every month. Frequent testing is useful when a number is expected to move and you want to see whether it does:

  • After a change to diet, exercise or cholesterol medication, to see how ApoB and LDL respond. Our ApoB test guide covers where to get it.
  • Borderline blood sugar. An HbA1c of 5.7% to 6.4% is in the prediabetes range. HbA1c reflects roughly the last 2 to 3 months, so quarterly testing matches how it works.
  • Testosterone therapy. The AUA guideline calls for checking levels after starting and then every 6 to 12 months. See our at-home testosterone test page.
  • GLP-1 medication, where people want to track lipids, liver markers and nutrients as weight falls. See the GLP-1 blood test guide.

If you are healthy and simply curious, two tests a year is plenty. Also remember that many insurance plans cover cholesterol screening and, for adults 40 to 70 who are overweight, type 2 diabetes screening at no cost when your doctor orders it.

A year on a blood test subscription: worked example

Worked example: four ApoB readings in 12 months

Take Dan, 52, a hypothetical reader whose doctor has just changed his cholesterol treatment. He wants an ApoB reading every three months to see how it responds, and to share each one with his doctor. On SiPhox quarterly he pays $124 for the first test (the advertised $99 plus $25 shipping) and $149 for each of the next three: $571 in year one, $596 after that, with 30 other markers on each test. On Function Health, $365 covers ApoB on two draws, so the other two readings have to come from somewhere else; adding two Labcorp OnDemand Complete Heart Health Tests at their $169 list price makes $703. On InsideTracker, the $489 Ultimate plan plus three member tests at $340 comes to $1,509. Rythm Health would be about $400 for four tests, but check its panel has the markers you want: it has no Lp(a) and uses fructosamine instead of HbA1c.

SiPhox Health results dashboard showing biomarker scores and trends
A subscription's main extra over one-off tests is the trend view: each result lands next to the last one. Image: SiPhox Health.

How the timing works in practice

Each SiPhox renewal ships a kit within about 3 days, it arrives in 3 to 5 days, you send it back overnight, and SiPhox quotes results 7 to 10 days after the lab receives it. From renewal to results is roughly two to three weeks by our count, so a quarterly cadence gives you a fresh number about every 13 weeks. Function Health quotes first results in about 48 hours after a Quest draw, but there are only two draws a year to wait for.

Five questions to answer before you subscribe

  1. Which markers do I want repeated? Write down two or three. If none needs repeating, a one-off test is cheaper.
  2. How often will the number actually change? HbA1c reflects about 2 to 3 months, so monthly HbA1c adds little; quarterly matches it.
  3. What is the all-in price per test? Add shipping, draw fees and add-ons. SiPhox's $124 is $149 with shipping.
  4. What does the intro price renew at? $99 becomes $124 on SiPhox; $59.25 becomes $79 on Rythm.
  5. Where do I cancel, and by when? On SiPhox, before the next kit ships; on Superpower, any time with the year running out.

How to pick a blood test subscription

If you want Pick Why
To test 4+ times a year at home, no needle SiPhox quarterly $149 per test, switch panels each cycle
The most markers per dollar, once or twice a year Function Health or Superpower 150 to 160+ markers for $349 to $365
Fast results and a small monthly panel Rythm Health 25+ markers, results within 48 hours of lab receipt
A doctor to review results Function Health Clinician notes included
To try before committing SiPhox one-off kit ($149) Same panels, no renewal

Still deciding between the two biggest names? Read SiPhox vs Function Health. You can pay for all of these with pre-tax money; see HSA and FSA blood tests.

Start with one test, keep what worksChoose a panel and a cadence, switch or cancel from your account. HSA and FSA cards accepted.
Check SiPhox price

Frequently asked questions

Is a blood test subscription worth it?

It is worth it if you will act on repeat results, for example tracking ApoB after a diet or medication change, HbA1c in the prediabetes range, or hormones on therapy. If you only want one baseline a year, a one-off test or a yearly membership is cheaper.

What is the cheapest blood test membership?

For a year of testing, SiPhox on a six-month cadence costs $298 for two 31-marker tests. Superpower ($349) and Function Health ($365) cost a little more but include far more markers across two lab draws.

Can I cancel SiPhox any time?

Yes. You can change your cadence or cancel from your account portal. Kits already shipped are not refunded, so cancel before your next ship date.

Can I pay for a blood test subscription with an HSA or FSA?

SiPhox, Function Health, Superpower, Rythm and InsideTracker all say their plans can be paid with HSA or FSA funds. Check with your plan administrator. See our HSA and FSA guide.

Does insurance cover blood test subscriptions?

No. Direct-to-consumer subscriptions are cash-pay. Insurance generally only covers lab work your doctor orders.

How often should I get blood work?

Healthy adults usually need routine blood work once a year or less. Testing every 1 to 3 months only makes sense when you are tracking a change, such as a new medication or a borderline result. Ask your doctor what interval suits you.

Written by the Home Blood Test Guide editorial team

We read the lab's own documentation, published validation studies and current price pages, and we cite every source below. Prices on this page were checked on September 29, 2026. Read our editorial policy.