Home Blood Test Guide

SiPhox cost in 2026: what you pay per test, per year and per biomarker

SiPhox Health costs $124 per test plus $25 shipping, so $149 all-in, and new members are offered the first test at $99 plus shipping. Testing quarterly on a core panel comes to $596 a year; Ultimate 360 is $274 per test.

SiPhox Health membership
SiPhox Health membership
From $124 + $25 shipping per test ($99 first test)

The sensible plans: a core panel every 6 months ($298 a year) or every 3 months ($596), with Ultimate 360 once a year if you want all 62 markers.

Check SiPhox price

Opens siphoxhealth.com in a new tab

Prices checked September 29, 2026

Every price here was read from SiPhox Health's pricing pages, shop, FAQ, terms and refund policy on September 29, 2026. SiPhox's own pages do not always agree (an older SiPhox article quotes a $225 Ultimate 360 total and different intro prices), so where they conflict we use the live pricing page and say so. See how we review.

SiPhox cost at a glance

The SiPhox price is $124 per test plus $25 US shipping, so $149 each time a kit ships. New members are offered the first test at $99 plus shipping ($124 all-in). You choose how often a kit comes, every month, every 3 months or every 6 months, and the membership renews on that schedule until you cancel.

$149Per test with shipping
$124First test for new members
$596Quarterly plan, per year
$274Ultimate 360 per test
Item Price
Membership, per test (any of the 4 core panels) $124
Shipping, per test $25 US, $50 Canada
First test for new members $99 + $25 shipping
Ultimate 360 upgrade +$125 per test ($274 all-in)
GLP Optimization upgrade +$75 per test ($224 all-in)
One-off kit, no membership $149 core panel, $274 Ultimate 360
Insurance Not accepted; HSA and FSA cards are

There is no separate monthly fee on top of this. The $124 covers the EasyDraw kit, the lab work, the dashboard and app, and the Sai AI assistant. Extra markers, coaching and a results review cost more, and all of them are priced below.

One conflict to know about: SiPhox's comparison and answers pages advertise "$99 for new customers, then renews at $124 + $25 shipping", while the homepage headline shows $124. Check which price your checkout shows before you pay.

See the current SiPhox priceCore panels are $124 a test plus $25 shipping, with the first test advertised at $99 for new members.
Check SiPhox price

SiPhox price per test, by panel

Every membership test includes one EasyDraw kit for one panel. The four core panels cost the same and you can switch between them each cycle. Two larger panels cost more per test. The table uses the $149 renewal price including shipping, and the last column divides it by the biomarkers SiPhox counts per test (which include calculated ratios).

Panel Biomarkers per test Upgrade cost Per test, with shipping Cost per biomarker
Longevity Essentials 31 Included $149 $4.81
Heart & Metabolic 28 Included $149 $5.32
Thyroid Focus 21 Included $149 $7.10
Hormone Focus 14 Included $149 $10.64
Ultimate 360 62 +$125 $274 $4.42
GLP Optimization 46 +$75 $224 $4.87
  • Best value per marker: Ultimate 360 at about $4.42 per biomarker, then Longevity Essentials at $4.81.
  • Most expensive per marker: Hormone Focus at $10.64, because it reports 14 markers for the same $149. It is still the one to pick if hormones are what you track, since it adds PSA, prolactin and progesterone.
  • Count conflicts: SiPhox's FAQ calls Ultimate 360 "60 biomarkers", while the panel page says 62 in the US and 52 in Canada. We use 62.
SiPhox cost per biomarker, by panel
Ultimate 360$4.42Longevity Essentials$4.81GLP Optimization$4.87Heart and Metabolic$5.32Thyroid Focus$7.10Hormone Focus$10.64

Our arithmetic from SiPhox prices checked 29 Sep 2026: price per test including $25 shipping divided by biomarkers per test (31, 28, 21, 14, 46 listed for GLP, 62 for Ultimate 360).

For the full marker list on each panel, see our guide to what SiPhox tests for or the panel section of our SiPhox Health review.

SiPhox cost per year at each cadence

Your yearly cost comes down to two choices: the panel and how often a kit ships. Here is the math at $149 per core test, $224 per GLP Optimization test and $274 per Ultimate 360 test, all including $25 US shipping.

Plan Monthly (12 tests) Quarterly (4 tests) Every 6 months (2 tests)
Core panel, list price $1,788 $596 $298
Core panel, first test at the $99 intro $1,763 $571 $273
GLP Optimization $2,688 $896 $448
Ultimate 360 $3,288 $1,096 $548
SiPhox yearly cost by number of tests
1 core test$1242 core tests (every 6 months)$2734 core tests (quarterly)$57112 core tests (monthly)$1,7634 Ultimate 360 tests$1,096

Our arithmetic from SiPhox prices checked 29 Sep 2026. Core rows use the $99 + $25 first test, then $124 + $25 per test. The Ultimate 360 row is $274 per test at list price.

How the intro row works: the first test is $99 + $25 = $124, then each renewal is $149. On a quarterly plan that is $124 + (3 x $149) = $571 for the first year. We could not confirm whether the $99 intro also applies when you upgrade the first test to GLP Optimization or Ultimate 360, so those rows use list price.

A common mix: Ultimate 360 once a year for the full picture, then Longevity Essentials the other three quarters to track ApoB, HbA1c, vitamin D and hormones. That costs $274 + (3 x $149) = $721 a year.

Prepay discounts: SiPhox's FAQ refers to members who "prepaid for the year", and its checkout data contains prepay discount settings of roughly 10% to 18% depending on plan. We could not confirm how or when these are offered, so look for a prepay option at checkout before you pick a cadence.

Canada: shipping is $50, so a core test is $174 and a quarterly year is $696.

Worked example: a first year that mixes panels

Take Priya, 50, who wants a broad baseline and then wants to follow the markers that move. January: Longevity Essentials at the new-member price, $124. April: Heart & Metabolic for kidney and liver markers, $149. July: Longevity Essentials again, $149. October: Ultimate 360 for the full 62 markers, $274. Her year costs $124 + $149 + $149 + $274 = $696. Paid from an HSA at a 22% federal tax rate, the real cost is about $543. If she had ticked the $45 CBC add-on and left it on every kit, the year would be $876, and if she had chosen Ultimate 360 every quarter it would be $1,096, $400 more than her mixed plan for a lot of markers she does not need to repeat.

To compare these totals with other services for the markers you actually care about, try our blood test cost calculator.

SiPhox add-ons and upgrades

At checkout SiPhox offers extras that are added to each test and recur until you remove them. These are the per-test prices in its pricing data on September 29, 2026. Not every add-on is offered on every panel.

Add-on Price per test What it adds
Complete blood count (CBC) +$45 Red and white cell counts and indices (EasyDraw kits only)
IGF-1 +$70 Growth hormone marker (EasyDraw kits only)
CBC + IGF-1 +$100 Both, $15 less than buying them separately
Wellness+ +$40 Extra metabolic, heart and nutrient markers
Hormone+, Thyroid+ or Metabolic+ +$50 each Stackable marker packs
Wellness & Thyroid+, Metabolic+ or Hormone+ +$75 each Wellness+ plus one focus pack
Advanced BioAge Report +$50 An overall biological age plus 9 system ages (Longevity and Heart panels)
Advanced GLP Assessment +$50 GLP Optimization and Ultimate 360 panels
Health Expert Results Review +$50 A health expert goes through your results with you

Because add-ons recur, a $45 CBC on a quarterly plan adds $180 a year. SiPhox's own affiliate page says 70% of customers upgrade during checkout, so decide what you need before you get there. If you only want advice once, a single Expert Health Coaching call is $50 as a one-time purchase.

One-off kits without a membership

If you only want to test once, the SiPhox shop sells kits with no subscription:

Product Price
Longevity Essentials, Heart & Metabolic, Thyroid Focus or Hormone Focus $149 each
Ultimate 360 $274
Kidney, Liver and Lp(a) Panel (12 markers) $85 (was $99)
Advanced Stress & Sleep Cortisol Test (4-point saliva) $120 (was $149)
295 Food & Environmental Allergy Panel (US only) $225 (was $249)
Advanced Gut Health Test $229 (was $249)
Expert Health Coaching, one credit $50 (was $70)
Prenuvo whole-body MRI + Ultimate 360 bundle $2,299

A one-off core kit lists at the same $149 as a membership test with shipping, but the shop does not show whether shipping is added on top, so check the total at checkout. One-off kits suit a single snapshot. The membership is the better deal if you will retest, because the first test can be $99 and your results trend in one dashboard. The $85 Lp(a), kidney and liver panel is the cheapest way to get a once-in-a-lifetime Lp(a) number from SiPhox.

HSA and FSA: the effective discount

SiPhox says every test is HSA and FSA eligible, and it will send an itemized receipt if your card is declined. HSA and FSA money goes in before federal income tax (IRS Publication 969), so paying with it cuts the real cost by your marginal tax rate. Here is what that means at the 22% and 32% federal brackets:

Purchase Price Real cost at 22% Real cost at 32%
First test (intro) $124 $96.72 (saves $27.28) $84.32 (saves $39.68)
One core test $149 $116.22 (saves $32.78) $101.32 (saves $47.68)
One Ultimate 360 test $274 $213.72 (saves $60.28) $186.32 (saves $87.68)
Quarterly core plan, one year $596 $464.88 (saves $131.12) $405.28 (saves $190.72)

That is federal income tax only; state tax savings, where your state gives them, come on top. SiPhox does not bill insurance. More on how this works across providers in our guide to HSA and FSA blood tests.

SiPhox cost per biomarker vs Function, Superpower and InsideTracker

Per test, SiPhox is cheap. Per year, it depends on what you count. The lab-draw memberships give you more distinct markers for less money, but only once or twice a year and only at a lab.

Plan Cost a year Markers Draws a year Cost per marker result Collection
SiPhox Longevity, every 6 months $298 31 per test (62 results) 2 $4.81 At home, upper arm
SiPhox Longevity, quarterly $596 31 per test (124 results) 4 $4.81 At home, upper arm
SiPhox Ultimate 360 once + Longevity x3 $721 62 distinct (155 results) 4 $4.65 At home, upper arm
Function Health $365 160+ lab tests 2 about $2.28 Quest venous draw
Superpower $349 150+ markers 2 about $2.33 Quest venous draw
InsideTracker Ultimate $489 about 48 1 about $10.19 Quest venous, or mobile draw +$119

There are two honest ways to read this. On distinct markers per dollar, Function Health and Superpower win clearly (see our Function Health cost breakdown). On repeat measurements of the markers that move, such as ApoB, HbA1c, testosterone and vitamin D, SiPhox gives you more data points for similar money and needs no lab visit. InsideTracker is the most expensive per marker of the four.

Cost per marker result over one year
Function Health$2.28Superpower$2.33SiPhox Ultimate 360 once + Longevity x3$4.65SiPhox Longevity quarterly$4.81InsideTracker Ultimate$10.19

Our arithmetic from list prices checked 29 Sep 2026: yearly price divided by marker results (Function $365 for 160+, Superpower $349 for 150+, SiPhox $721 for 155 and $596 for 124, InsideTracker $489 for about 48).

Head-to-heads: SiPhox vs Function Health and SiPhox vs Superpower.

One more cost to count: speed. SiPhox quotes 7 to 10 days after the lab receives the sample, and with up to 3 days for the kit to ship, 3 to 5 days in transit and an overnight return, order to results is about 2 to 3 weeks. Function Health quotes first results in about 48 hours and Labcorp OnDemand 1 to 2 business days after a lab visit. If you need a number this week, paying less per marker at a lab may be worth the needle.

How the SiPhox price has changed

SiPhox has repriced several times, which is why older reviews quote numbers that no longer match checkout. The trend is more markers per test for a similar price.

When Price Markers per test Source
July 2023 $95 kit plus $16 a month membership 17 TechCrunch
Earlier pricing record $125 per cycle with free US shipping not stated Inactive price data on siphoxhealth.com
February 2025 $150 mail-in kit 14 Boston Globe
September 2026 $124 + $25 shipping ($99 first test) 31 on Longevity Essentials SiPhox pricing page

At the February 2025 figure, $150 for 14 markers, each marker cost about $10.71. At today's $149 for 31 on Longevity Essentials it is $4.81. The catch is that free shipping has gone: the $25 per kit is now charged separately, and it adds $100 a year on a quarterly plan.

Which SiPhox plan fits your budget

Match the plan to what you are trying to learn. Most people overspend by testing too often or by leaving an add-on on every kit.

If you want Choose Cost Why
One snapshot, no subscription One-off core kit $149 No renewal to cancel
An Lp(a) number, which rarely changes Kidney, Liver and Lp(a) panel $85 12 markers, the cheapest SiPhox route to Lp(a)
A check-in twice a year Longevity Essentials every 6 months $273 year one, $298 after Enough to see a trend in ApoB, HbA1c and vitamin D
To track a diet, training or medication change Longevity Essentials quarterly $571 year one, $596 after HbA1c reflects roughly 3 months, so quarterly lines up with it
Hormone monitoring, for example on TRT Hormone Focus, alternating with Longevity Essentials $571 year one, $596 after Hormone Focus adds PSA and prolactin; Longevity adds hematocrit and lipids
Monitoring on GLP-1 medication GLP Optimization quarterly $896 a year Liver, kidney, iron, B12 and folate alongside metabolic markers
The full picture once, then tracking Ultimate 360 once + Longevity Essentials x3 $696 year one, $721 after 62 markers once, the 31 that move three more times
The most markers per dollar, once a year, and a lab visit is fine Function Health or Superpower $349 to $365 150 to 160+ markers across two venous draws

The last row is not SiPhox, and that is the honest answer for someone who wants breadth once a year. For everyone who wants to retest at home, the Longevity Essentials rows are where the value is.

Renewals, cancellation and refunds

  • Auto-renewal: SiPhox's terms say the subscription "will continue to automatically renew indefinitely" until you cancel. You are charged on your cadence: every month, 3 months or 6 months.
  • Cancel or change cadence: from your account portal at any time. To stop a kit that has not shipped yet, email support@siphoxhealth.com to cancel the membership and the shipment.
  • Monthly plans: if you cancel mid-month you keep membership benefits to the end of the month you paid for.
  • Not refundable: any period in which a kit has already shipped. Kits cannot be returned.
  • Partial results: no automatic credit. SiPhox may send a replacement kit for the missing markers, give account credit, or offer nothing if most of the panel was reported (refund policy updated February 2, 2026).
  • Disputes: the terms include binding arbitration, with 30 days to opt out after you sign up.
Set a renewal reminder

Surprise $124 renewals and double charges came up in 6 of the 20 most recent one-star Trustpilot reviews we read. Put your next renewal date in your calendar the day you order, and cancel before it if you do not want the next kit.

The company side of these complaints is covered in is SiPhox legit.

Is SiPhox worth the money?

For most people who buy it, yes, on a 6-monthly or quarterly plan. $298 to $596 a year buys you ApoB, Lp(a), hs-CRP, HbA1c, hormones, thyroid and vitamin D from an upper-arm draw at home, as often as you want to track them. That is the case for people who avoid needles, live far from a lab, or are on a treatment that needs regular monitoring such as GLP-1 medication or TRT.

It is poor value if you want the biggest possible panel once a year and do not mind a lab visit. Function Health or Superpower cost about the same as a SiPhox quarterly plan and report two to three times as many distinct markers. And the monthly plan, at $1,788 a year on a core panel, is more testing than most healthy adults need.

Before you order, check our SiPhox discount code page for the offers that actually work.

Check today's SiPhox price$99 first test for new members, then $124 plus $25 shipping per test. Change your cadence or cancel from your account.
See SiPhox plans

Frequently asked questions

How much is SiPhox Health per month?

There is no monthly fee unless you choose monthly testing. On a monthly plan you pay $149 per kit ($124 plus $25 shipping), or $1,788 a year. On a quarterly plan you pay $149 every three months, which works out to about $50 a month.

How much is the SiPhox membership?

$124 per test plus $25 US shipping. The membership itself has no extra fee; you pay each time a kit ships. New members are offered the first test for $99 plus shipping.

How much does SiPhox Ultimate 360 cost?

$274 per test: the $124 membership, a $125 Ultimate 360 upgrade and $25 shipping. It is also sold as a one-off kit for $274. Testing Ultimate 360 every quarter costs $1,096 a year.

Does SiPhox charge for shipping?

Yes. Shipping is $25 per test in the US and $50 in Canada, charged on every kit. Older SiPhox pricing included free US shipping, which is why some reviews quote $125 all-in.

Can I use my HSA or FSA for SiPhox?

Yes. SiPhox says all its tests are HSA and FSA eligible and it will provide an itemized receipt if your card is declined. At a 22% federal tax rate that makes a $149 test cost about $116 in real terms.

Is there a SiPhox free trial?

No. The cheapest way in is the $99 first test for new members ($124 with shipping). You can cancel before the next renewal, but a kit that has shipped is not refundable.

Written by the Home Blood Test Guide editorial team

We read the lab's own documentation, published validation studies and current price pages, and we cite every source below. Prices on this page were checked on September 29, 2026. Read our editorial policy.