Quick answer
At home blood test cost depends on how many markers you want and how the blood is taken. On September 29, 2026: a single marker ordered online with a lab visit starts at $39 (HbA1c at Labcorp OnDemand); a broad at-home panel from SiPhox is $149 per test all-in for 14 to 31 markers, or $274 for 62; wellness panels at a lab run $189 to $405; and yearly memberships with two lab draws cost $349 to $399. Insurance generally does not cover any of these, but most accept HSA and FSA cards, which cuts the real cost by your tax rate.
At home blood test cost by type
| Type | Example | Price | Markers | Collection |
|---|---|---|---|---|
| Single test, ordered online | Labcorp OnDemand HbA1c | $39 | 1 | Lab visit |
| Single panel, ordered online | Labcorp CMP / lipid panel / TSH and free T4 | $49 / $59 / $89 | 2 to 14 | Lab visit |
| At-home kit, arm device | SiPhox core panel | $149 with shipping | 14 to 31 | At home, no needle |
| At-home kit, arm device | SiPhox Ultimate 360 | $274 with shipping | 62 | At home, no needle |
| At-home kit, arm device | Rythm Health | $79 per test plus shipping | 25+ | At home |
| Wellness panel at a lab | Labcorp Comprehensive Health Test | $189 | CMP, CBC, lipids, HbA1c, urinalysis | Lab visit |
| Wellness panel at a lab | Quest Comprehensive Health Profile | $329 + $6 physician fee | 75+ | Lab visit or $79 home draw |
| Yearly membership | Superpower / Function Health | $349 / $365 a year | 150+ / 160+ a year | 2 Quest draws |
| Yearly membership | Everlywell 360 | $399 a year | 83 | Quest draw |
Prices from each company's site on September 29, 2026. Labcorp and Quest run frequent sales, so their prices move more than the subscription services.
Cost per biomarker
The fairest way to compare panels of different sizes is cost per marker. SiPhox's panels, with $25 shipping included:
| Panel | Biomarkers per test | Upgrade cost | Per test, with shipping | Cost per biomarker |
|---|---|---|---|---|
| Longevity Essentials | 31 | Included | $149 | $4.81 |
| Heart & Metabolic | 28 | Included | $149 | $5.32 |
| Thyroid Focus | 21 | Included | $149 | $7.10 |
| Hormone Focus | 14 | Included | $149 | $10.64 |
| Ultimate 360 | 62 | +$125 | $274 | $4.42 |
| GLP Optimization | 46 | +$75 | $224 | $4.87 |
And the wider market, per test or per year:
| Service | Cost | Markers | Cost per marker |
|---|---|---|---|
| Function Health | $365 a year | 160+ | about $2.28 |
| Superpower | $349 a year | 150+ | about $2.33 |
| Rythm Health | about $100 per test all-in (reported) | 27 (men), 28 (women) | about $3.70 |
| Quest Comprehensive (men's) | $335 with fee | 75+ | about $4.47 |
| SiPhox Ultimate 360 | $274 per test | 62 | about $4.42 |
| SiPhox Longevity Essentials | $149 per test | 31 | about $4.81 |
| Everlywell 360 | $399 a year | 83 | about $4.81 |
| InsideTracker Ultimate | $489 | up to about 48 | about $10.19 |
Our arithmetic from prices checked 29 Sep 2026: price including shipping or fees divided by advertised marker count (Function 160, Superpower 150, Quest 75 at the minimum of each "+" figure). Lab-draw memberships spread one price over two draws a year.
Two caveats. Counts include calculated ratios on some services (SiPhox counts ratios like ApoB:ApoA1), so a lower cost per marker is not always more information. And the cheapest per marker is not the cheapest way to get the few markers you care about, especially if you want them more than twice a year. Run your own list through the blood test cost calculator.
Why prices vary so much
Most of the price difference between services is not the lab chemistry. It comes from four things:
- How the blood is collected. A lab visit uses a phlebotomist the lab already pays for. An at-home kit has to include collection hardware, a cold pack, an insulated mailer and overnight return shipping, which is why SiPhox charges $25 for shipping alone. A mobile phlebotomist coming to your home costs $79 to $119 extra.
- How many markers share one sample. Adding a marker to a sample that is already in the analyzer costs the lab little. That is why big panels like Function Health's work out at about $2 a marker while single tests cost $39 or more.
- Physician oversight. Direct-to-consumer lab orders still need a clinician to sign off. Quest shows this as a $6 fee; others build it into the price.
- Software and support. Memberships pay for dashboards, trend tracking, coaching and apps. You may or may not value those.
So the fair question is not "which test is cheapest" but "which test gives me the markers I want, collected the way I want, as often as I want, for the least money."
Cheapest way to test common markers
If you only want one or two specific markers, a single test ordered online is usually cheaper than a panel. List prices from Labcorp OnDemand on September 29, 2026 (they run frequent sales):
| You want | Cheapest single option we found | At-home alternative |
|---|---|---|
| HbA1c | Labcorp HbA1c, $39 | SiPhox Longevity or Heart, $149, plus 27 to 30 other markers |
| Lipid panel | Labcorp lipid panel, $59 | SiPhox Longevity, with ApoB and Lp(a) added |
| ApoB | Labcorp Complete Heart Health Test, $169 | SiPhox Longevity or Heart, $149 |
| Kidney and liver | Labcorp CMP, $49 | SiPhox Heart & Metabolic, $149 (7 of the 14 CMP markers) |
| Thyroid | Labcorp TSH and free T4, $89 | SiPhox Thyroid Focus, $149, with free T3 and antibodies |
| Progesterone | Labcorp progesterone, $89 | SiPhox Hormone Focus, $149, 14 hormone markers |
The pattern: a single lab test wins for one marker you need once. An at-home panel wins when you want several markers together, no lab visit, or repeat testing. See the at-home A1C test and at-home cholesterol test guides for more single-marker options.
Is an at home blood test covered by insurance?
Usually not. Direct-to-consumer tests are sold as cash-pay: SiPhox says it does not accept insurance, and Quest says tests bought on questhealth.com are for people who want to pay directly and not seek reimbursement from their insurer. Function Health, Superpower and Everlywell 360 are also self-pay memberships.
What insurance does cover is lab work your doctor orders as part of your care. Under the ACA, plans must cover some screening blood tests at no cost in network, including cholesterol screening for adults of certain ages or higher risk, type 2 diabetes screening for adults 40 to 70 who are overweight or obese, hepatitis C screening for adults 18 to 79 and HIV screening for ages 15 to 65. If you only need the basics, asking for them at your annual physical is the cheapest route. The home services are for markers doctors rarely order (ApoB, Lp(a), a full hormone panel) or for testing more often.
HSA and FSA
Almost every service here accepts HSA and FSA cards: SiPhox, Function Health, Superpower, InsideTracker, Rythm and Labcorp OnDemand all say so, and Quest accepts the cards but leaves eligibility to your plan administrator. IRS Publication 502 counts laboratory fees that are part of medical care as qualified expenses. Paying pre-tax means a $149 test effectively costs about $97 to $116 if your combined tax rate is 22% to 35%. Full details, including receipts, in HSA eligible blood tests.
Hidden costs to check before you buy
- Shipping. SiPhox adds $25 per test in the US and $50 to Canada, on every renewal.
- At-home draw fees. Quest Mobile adds $79; InsideTracker's mobile draw adds $119; Function and Superpower charge extra for at-home draws.
- Physician fees. Quest adds a $6 physician service fee per order.
- Auto-renewal. Subscriptions keep billing until you cancel. See blood test subscriptions for the renewal rules.
- Add-ons. On SiPhox, a CBC is +$45, IGF-1 +$70, and an expert results review +$50 per test.
- Failed samples. A home sample that does not have enough blood may mean a redraw kit, a credit or, at the company's discretion, nothing. SiPhox does not refund a period once the kit has shipped.
- Follow-up. An abnormal result may need a doctor visit and a confirmatory lab test.
A quick checklist before you pay
- Is the price per test or per year, and does it include shipping and any physician fee?
- Is there an intro price, and what does it renew at?
- Does it collect at home, at a lab, or at home for an extra fee?
- Which of the markers you actually want are on it?
- Can you pay with an HSA or FSA card?
Worked examples
Tracking ApoB four times a year
SiPhox quarterly: 4 x $149 = $596, with 30 other markers each time and no lab visits. Labcorp's Complete Heart Health Test with ApoB at its $169 list price: 4 x $169 = $676, four lab visits. Function Health includes ApoB but only on its two draws a year. Our ApoB test guide lists more options.
One big baseline this year
Superpower at $349 or Function at $365 gives the most markers for one year of money, if a Quest draw is fine. SiPhox Ultimate 360 once is $274 for 62 markers at home. Labcorp's Comprehensive Health Test is $189 for the standard CMP, CBC, lipids and HbA1c set; see our full body blood test guide for what each covers.
Thyroid only
Labcorp TSH and free T4: $89, 2 markers. SiPhox Thyroid Focus: $149, 21 markers including free T3 and both thyroid antibodies. See the at-home thyroid test guide.
What one, two, four and twelve tests cost
The number of tests you want in a year changes the cheapest answer more than anything else. On SiPhox Longevity Essentials, with the advertised $99 first test plus $25 shipping and $149 after that, one test costs $124, two cost $273, four cost $571 and twelve cost $1,763. On InsideTracker, the $489 Ultimate plan plus $340 per extra member test makes one test $489, two $829 and four $1,509.
Our arithmetic from prices checked 29 Sep 2026. Function Health and Superpower include two draws a year, so four tests is not a like-for-like option there. Rythm per-test cost is a reported all-in figure.
Which option fits your budget
| If you want | Choose | What you pay |
|---|---|---|
| One marker, once, and a lab visit is fine | A single Labcorp OnDemand test | $39 (HbA1c) to $89 (TSH and free T4) |
| Routine blood work without insurance | Labcorp Comprehensive Health Test | $189 |
| The most markers per dollar in one year | Superpower or Function Health | $349 or $365, about $2.30 a marker |
| Everything SiPhox measures in one needle-free test | SiPhox Ultimate 360 | $274, about $4.42 a marker |
| Heart, metabolic and hormone markers repeated at home | SiPhox Longevity Essentials, quarterly | $149 a test, $571 in year one |
Paying from an HSA or FSA lowers every figure above by your tax rate; the HSA and FSA guide works that through. For SiPhox's own prices at every cadence, see SiPhox cost.
Frequently asked questions
How much is an at home blood test?
Single markers ordered online start around $39, at-home panels from SiPhox cost $149 per test (14 to 31 markers) or $274 (62 markers), and yearly lab-draw memberships cost $349 to $399.
Is an at home blood test covered by insurance?
Generally no. Direct-to-consumer tests are cash-pay. Insurance covers lab work your doctor orders, and some screening tests are free in network under the ACA.
How much does blood work cost without insurance?
Ordered directly, a CMP costs about $49 and a lipid panel about $59 at Labcorp OnDemand, and a combined CMP, CBC, lipid, HbA1c and urinalysis panel is $189. Broader wellness panels at Quest cost $329 to $399 plus a $6 fee.
Can I use my HSA or FSA for an at home blood test?
Usually yes. SiPhox, Function Health, Superpower, InsideTracker, Rythm and Labcorp OnDemand accept HSA and FSA payment. Check eligibility with your plan administrator.
Is a cheaper blood test less accurate?
Not necessarily. Price mostly reflects collection method, shipping and software. Accuracy depends on the lab, the sample quality and the marker. Check that the lab is CLIA-certified and CAP-accredited.
What is the cheapest way to get a lot of biomarkers?
Per marker, the yearly memberships are cheapest: about $2.28 on Function Health and $2.33 on Superpower. If you want to test at home or more than twice a year, SiPhox costs about $4.42 to $4.81 per marker on its larger panels.
Sources
- SiPhox Health: membership, panels and pricing (checked 29 Sep 2026)
- SiPhox Health FAQ
- SiPhox: how much is at-home blood testing (SiPhox answers, April 2026)
- SiPhox Health shop: one-off kits and add-ons
- Labcorp OnDemand: general health test prices
- Labcorp OnDemand: Comprehensive Health Test
- Labcorp OnDemand: HSA and FSA eligible tests
- Quest: Comprehensive Health Profile, Men's
- Quest: Elite Health Profile
- Quest: payment options, HSA/FSA and insurance FAQ
- Function Health: pricing (checked 29 Sep 2026)
- Superpower: membership and pricing (checked 29 Sep 2026)
- Rythm Health: pricing and plans (checked 29 Sep 2026)
- Everlywell: Everlywell 360 and single test kits (checked 29 Sep 2026)
- InsideTracker: membership price and renewal terms
- InsideTracker: Ultimate plan
- HealthCare.gov: preventive care benefits for adults
- IRS Publication 502 (2025): medical and dental expenses