Home Blood Test Guide

At home blood test cost in 2026: prices, cost per biomarker and insurance

An at home blood test costs $39 to $89 for a single marker ordered online, $149 to $274 for a 14 to 62 marker SiPhox kit, and $349 to $399 a year for lab-draw memberships. Insurance rarely pays for direct-to-consumer tests, but HSA and FSA cards usually work.

SiPhox Longevity Essentials
SiPhox Longevity Essentials
From $124 + $25 shipping per test

31 biomarkers including ApoB, Lp(a), hs-CRP and HbA1c for $149 all-in, about $4.81 per marker, collected at home with no needle.

Check SiPhox price

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Quick answer

At home blood test cost depends on how many markers you want and how the blood is taken. On September 29, 2026: a single marker ordered online with a lab visit starts at $39 (HbA1c at Labcorp OnDemand); a broad at-home panel from SiPhox is $149 per test all-in for 14 to 31 markers, or $274 for 62; wellness panels at a lab run $189 to $405; and yearly memberships with two lab draws cost $349 to $399. Insurance generally does not cover any of these, but most accept HSA and FSA cards, which cuts the real cost by your tax rate.

from $39Single marker at a lab
$149SiPhox 31-marker kit, all-in
$349 to $399Yearly lab-draw memberships
about $2.28Lowest cost per marker
$149 all-in for 31 biomarkersSiPhox Longevity Essentials: ApoB, Lp(a), hs-CRP, HbA1c, hormones, vitamin D and ferritin from one needle-free arm draw.
See SiPhox plans

At home blood test cost by type

Type Example Price Markers Collection
Single test, ordered online Labcorp OnDemand HbA1c $39 1 Lab visit
Single panel, ordered online Labcorp CMP / lipid panel / TSH and free T4 $49 / $59 / $89 2 to 14 Lab visit
At-home kit, arm device SiPhox core panel $149 with shipping 14 to 31 At home, no needle
At-home kit, arm device SiPhox Ultimate 360 $274 with shipping 62 At home, no needle
At-home kit, arm device Rythm Health $79 per test plus shipping 25+ At home
Wellness panel at a lab Labcorp Comprehensive Health Test $189 CMP, CBC, lipids, HbA1c, urinalysis Lab visit
Wellness panel at a lab Quest Comprehensive Health Profile $329 + $6 physician fee 75+ Lab visit or $79 home draw
Yearly membership Superpower / Function Health $349 / $365 a year 150+ / 160+ a year 2 Quest draws
Yearly membership Everlywell 360 $399 a year 83 Quest draw

Prices from each company's site on September 29, 2026. Labcorp and Quest run frequent sales, so their prices move more than the subscription services.

Cost per biomarker

The fairest way to compare panels of different sizes is cost per marker. SiPhox's panels, with $25 shipping included:

Panel Biomarkers per test Upgrade cost Per test, with shipping Cost per biomarker
Longevity Essentials 31 Included $149 $4.81
Heart & Metabolic 28 Included $149 $5.32
Thyroid Focus 21 Included $149 $7.10
Hormone Focus 14 Included $149 $10.64
Ultimate 360 62 +$125 $274 $4.42
GLP Optimization 46 +$75 $224 $4.87

And the wider market, per test or per year:

Service Cost Markers Cost per marker
Function Health $365 a year 160+ about $2.28
Superpower $349 a year 150+ about $2.33
Rythm Health about $100 per test all-in (reported) 27 (men), 28 (women) about $3.70
Quest Comprehensive (men's) $335 with fee 75+ about $4.47
SiPhox Ultimate 360 $274 per test 62 about $4.42
SiPhox Longevity Essentials $149 per test 31 about $4.81
Everlywell 360 $399 a year 83 about $4.81
InsideTracker Ultimate $489 up to about 48 about $10.19
Cost per biomarker, by service and panel
Function Health$2.28Superpower$2.33Rythm Health$3.7SiPhox Ultimate 360$4.42Quest Comprehensive (men)$4.47SiPhox Longevity Essentials$4.81Everlywell 360$4.81SiPhox GLP Optimization$4.87SiPhox Heart and Metabolic$5.32SiPhox Thyroid Focus$7.1InsideTracker Ultimate$10.19SiPhox Hormone Focus$10.64

Our arithmetic from prices checked 29 Sep 2026: price including shipping or fees divided by advertised marker count (Function 160, Superpower 150, Quest 75 at the minimum of each "+" figure). Lab-draw memberships spread one price over two draws a year.

Two caveats. Counts include calculated ratios on some services (SiPhox counts ratios like ApoB:ApoA1), so a lower cost per marker is not always more information. And the cheapest per marker is not the cheapest way to get the few markers you care about, especially if you want them more than twice a year. Run your own list through the blood test cost calculator.

Why prices vary so much

Most of the price difference between services is not the lab chemistry. It comes from four things:

  • How the blood is collected. A lab visit uses a phlebotomist the lab already pays for. An at-home kit has to include collection hardware, a cold pack, an insulated mailer and overnight return shipping, which is why SiPhox charges $25 for shipping alone. A mobile phlebotomist coming to your home costs $79 to $119 extra.
  • How many markers share one sample. Adding a marker to a sample that is already in the analyzer costs the lab little. That is why big panels like Function Health's work out at about $2 a marker while single tests cost $39 or more.
  • Physician oversight. Direct-to-consumer lab orders still need a clinician to sign off. Quest shows this as a $6 fee; others build it into the price.
  • Software and support. Memberships pay for dashboards, trend tracking, coaching and apps. You may or may not value those.

So the fair question is not "which test is cheapest" but "which test gives me the markers I want, collected the way I want, as often as I want, for the least money."

Cheapest way to test common markers

If you only want one or two specific markers, a single test ordered online is usually cheaper than a panel. List prices from Labcorp OnDemand on September 29, 2026 (they run frequent sales):

You want Cheapest single option we found At-home alternative
HbA1c Labcorp HbA1c, $39 SiPhox Longevity or Heart, $149, plus 27 to 30 other markers
Lipid panel Labcorp lipid panel, $59 SiPhox Longevity, with ApoB and Lp(a) added
ApoB Labcorp Complete Heart Health Test, $169 SiPhox Longevity or Heart, $149
Kidney and liver Labcorp CMP, $49 SiPhox Heart & Metabolic, $149 (7 of the 14 CMP markers)
Thyroid Labcorp TSH and free T4, $89 SiPhox Thyroid Focus, $149, with free T3 and antibodies
Progesterone Labcorp progesterone, $89 SiPhox Hormone Focus, $149, 14 hormone markers

The pattern: a single lab test wins for one marker you need once. An at-home panel wins when you want several markers together, no lab visit, or repeat testing. See the at-home A1C test and at-home cholesterol test guides for more single-marker options.

Is an at home blood test covered by insurance?

Usually not. Direct-to-consumer tests are sold as cash-pay: SiPhox says it does not accept insurance, and Quest says tests bought on questhealth.com are for people who want to pay directly and not seek reimbursement from their insurer. Function Health, Superpower and Everlywell 360 are also self-pay memberships.

What insurance does cover is lab work your doctor orders as part of your care. Under the ACA, plans must cover some screening blood tests at no cost in network, including cholesterol screening for adults of certain ages or higher risk, type 2 diabetes screening for adults 40 to 70 who are overweight or obese, hepatitis C screening for adults 18 to 79 and HIV screening for ages 15 to 65. If you only need the basics, asking for them at your annual physical is the cheapest route. The home services are for markers doctors rarely order (ApoB, Lp(a), a full hormone panel) or for testing more often.

HSA and FSA

Almost every service here accepts HSA and FSA cards: SiPhox, Function Health, Superpower, InsideTracker, Rythm and Labcorp OnDemand all say so, and Quest accepts the cards but leaves eligibility to your plan administrator. IRS Publication 502 counts laboratory fees that are part of medical care as qualified expenses. Paying pre-tax means a $149 test effectively costs about $97 to $116 if your combined tax rate is 22% to 35%. Full details, including receipts, in HSA eligible blood tests.

Hidden costs to check before you buy

  • Shipping. SiPhox adds $25 per test in the US and $50 to Canada, on every renewal.
  • At-home draw fees. Quest Mobile adds $79; InsideTracker's mobile draw adds $119; Function and Superpower charge extra for at-home draws.
  • Physician fees. Quest adds a $6 physician service fee per order.
  • Auto-renewal. Subscriptions keep billing until you cancel. See blood test subscriptions for the renewal rules.
  • Add-ons. On SiPhox, a CBC is +$45, IGF-1 +$70, and an expert results review +$50 per test.
  • Failed samples. A home sample that does not have enough blood may mean a redraw kit, a credit or, at the company's discretion, nothing. SiPhox does not refund a period once the kit has shipped.
  • Follow-up. An abnormal result may need a doctor visit and a confirmatory lab test.

A quick checklist before you pay

  1. Is the price per test or per year, and does it include shipping and any physician fee?
  2. Is there an intro price, and what does it renew at?
  3. Does it collect at home, at a lab, or at home for an extra fee?
  4. Which of the markers you actually want are on it?
  5. Can you pay with an HSA or FSA card?

Worked examples

Tracking ApoB four times a year

SiPhox quarterly: 4 x $149 = $596, with 30 other markers each time and no lab visits. Labcorp's Complete Heart Health Test with ApoB at its $169 list price: 4 x $169 = $676, four lab visits. Function Health includes ApoB but only on its two draws a year. Our ApoB test guide lists more options.

One big baseline this year

Superpower at $349 or Function at $365 gives the most markers for one year of money, if a Quest draw is fine. SiPhox Ultimate 360 once is $274 for 62 markers at home. Labcorp's Comprehensive Health Test is $189 for the standard CMP, CBC, lipids and HbA1c set; see our full body blood test guide for what each covers.

Thyroid only

Labcorp TSH and free T4: $89, 2 markers. SiPhox Thyroid Focus: $149, 21 markers including free T3 and both thyroid antibodies. See the at-home thyroid test guide.

What one, two, four and twelve tests cost

The number of tests you want in a year changes the cheapest answer more than anything else. On SiPhox Longevity Essentials, with the advertised $99 first test plus $25 shipping and $149 after that, one test costs $124, two cost $273, four cost $571 and twelve cost $1,763. On InsideTracker, the $489 Ultimate plan plus $340 per extra member test makes one test $489, two $829 and four $1,509.

Four tests in one year, by service
Rythm Health (about $100 all-in)$400SiPhox Longevity, year one$571SiPhox Longevity, list price$596Labcorp Complete Heart Health x 4$676SiPhox Ultimate 360 x 4$1,096InsideTracker Ultimate + 3 tests$1,509

Our arithmetic from prices checked 29 Sep 2026. Function Health and Superpower include two draws a year, so four tests is not a like-for-like option there. Rythm per-test cost is a reported all-in figure.

The range of SiPhox Health EasyDraw test kit boxes
SiPhox's six panels share one price for the four core kits ($149 with shipping) and charge more for GLP Optimization ($224) and Ultimate 360 ($274). Image: SiPhox Health.

Which option fits your budget

If you want Choose What you pay
One marker, once, and a lab visit is fine A single Labcorp OnDemand test $39 (HbA1c) to $89 (TSH and free T4)
Routine blood work without insurance Labcorp Comprehensive Health Test $189
The most markers per dollar in one year Superpower or Function Health $349 or $365, about $2.30 a marker
Everything SiPhox measures in one needle-free test SiPhox Ultimate 360 $274, about $4.42 a marker
Heart, metabolic and hormone markers repeated at home SiPhox Longevity Essentials, quarterly $149 a test, $571 in year one

Paying from an HSA or FSA lowers every figure above by your tax rate; the HSA and FSA guide works that through. For SiPhox's own prices at every cadence, see SiPhox cost.

Price it against your own listLongevity Essentials $124 plus $25 shipping per test, Ultimate 360 $274 all-in. HSA and FSA accepted.
Check SiPhox price

Frequently asked questions

How much is an at home blood test?

Single markers ordered online start around $39, at-home panels from SiPhox cost $149 per test (14 to 31 markers) or $274 (62 markers), and yearly lab-draw memberships cost $349 to $399.

Is an at home blood test covered by insurance?

Generally no. Direct-to-consumer tests are cash-pay. Insurance covers lab work your doctor orders, and some screening tests are free in network under the ACA.

How much does blood work cost without insurance?

Ordered directly, a CMP costs about $49 and a lipid panel about $59 at Labcorp OnDemand, and a combined CMP, CBC, lipid, HbA1c and urinalysis panel is $189. Broader wellness panels at Quest cost $329 to $399 plus a $6 fee.

Can I use my HSA or FSA for an at home blood test?

Usually yes. SiPhox, Function Health, Superpower, InsideTracker, Rythm and Labcorp OnDemand accept HSA and FSA payment. Check eligibility with your plan administrator.

Is a cheaper blood test less accurate?

Not necessarily. Price mostly reflects collection method, shipping and software. Accuracy depends on the lab, the sample quality and the marker. Check that the lab is CLIA-certified and CAP-accredited.

What is the cheapest way to get a lot of biomarkers?

Per marker, the yearly memberships are cheapest: about $2.28 on Function Health and $2.33 on Superpower. If you want to test at home or more than twice a year, SiPhox costs about $4.42 to $4.81 per marker on its larger panels.

Written by the Home Blood Test Guide editorial team

We read the lab's own documentation, published validation studies and current price pages, and we cite every source below. Prices on this page were checked on September 29, 2026. Read our editorial policy.