Quick answer: the hemoglobin normal range is 13.8 to 17.2 g/dL (138 to 172 g/L) for adult men and 12.1 to 15.1 g/dL (121 to 151 g/L) for adult women, according to MedlinePlus. The WHO's 2024 guideline keeps its anemia cutoffs at under 13.0 g/dL for men and under 12.0 g/dL for non-pregnant women. To convert g/dL to g/L, multiply by 10.
Hemoglobin normal range
MedlinePlus Medical Encyclopedia, hemoglobin test.
| Group | Normal (MedlinePlus) | Anemia cutoff (WHO 2024) |
|---|---|---|
| Adult men | 13.8 to 17.2 g/dL | Under 13.0 g/dL (130 g/L) |
| Adult non-pregnant women | 12.1 to 15.1 g/dL | Under 12.0 g/dL (120 g/L) |
| Pregnancy | Lower | Separate, lower cutoffs by trimester |
| Newborns | 14 to 24 g/dL | Not covered here |
The MedlinePlus CBC article uses a slightly wider adult range (13 to 18 g/dL for men, 12 to 16 for women), a reminder that each lab sets its own. MedlinePlus also notes the range can vary with age, sex, altitude and smoking: people living at high altitude and smokers run higher.
What hemoglobin does
Hemoglobin is the iron-containing protein inside red blood cells that carries oxygen from the lungs to the rest of the body. It is the core number in a complete blood count, alongside hematocrit, red cell count and the red cell indices (MCV, MCH, MCHC). A hemoglobin result tells you how much oxygen-carrying capacity you have, but not why it is low or high; that takes other tests, such as ferritin and iron studies.
What low hemoglobin means
Low hemoglobin is anemia. MedlinePlus lists these causes:
- Iron deficiency, a common cause, and blood loss from injury or heavy periods
- Lack of vitamin B12 or folate
- Thalassemia and other inherited conditions
- Chronic kidney disease, liver disease, cancer and other long-term illness
- Bone marrow problems, including leukemia and drug or radiation toxicity
Symptoms such as tiredness, shortness of breath on exertion or pale skin with a low hemoglobin need a doctor. Our blood test for fatigue guide covers which markers to check first.
What high hemoglobin means
MedlinePlus lists lung disease, heart disease, sleep apnea and polycythemia vera (a bone marrow disease that makes too many red cells) as causes of a high hemoglobin. Dehydration, smoking and living at altitude raise it too. Testosterone therapy is another common reason: the Endocrine Society's guideline lists an elevated hematocrit as a reason not to start testosterone and tells doctors to monitor hematocrit during treatment. See our TRT blood test guide.
Worked example
A 34-year-old woman with heavy periods gets a hemoglobin of 11.4 g/dL (114 g/L). That is under both the MedlinePlus range (12.1 to 15.1) and the WHO anemia cutoff of 12.0. The next step is ferritin: if hers is 9 ng/mL, iron deficiency is the likely cause, and her doctor can look for the source and plan treatment. Rechecking hemoglobin 8 to 12 weeks after treatment starts shows whether it is working.
A 52-year-old man on testosterone therapy has a hemoglobin of 17.9 g/dL, above the MedlinePlus limit of 17.2, with a hematocrit of 53%. That pattern is what his prescriber monitors on therapy; the dose or plan may need to change.
Which test to use
| If you want | Test | Where |
|---|---|---|
| A hemoglobin trend alongside heart and hormone markers | Hemoglobin and calculated hematocrit | SiPhox Longevity Essentials |
| To find the cause of low hemoglobin | Ferritin, iron, TIBC, B12, folate | SiPhox Ultimate 360 or GLP Optimization |
| A full blood count with red cell indices | CBC | SiPhox +${money(PRICE.cbc)} CBC add-on, or your doctor |
| Hematocrit monitoring on testosterone | Hemoglobin, hematocrit, testosterone, estradiol | SiPhox Longevity Essentials plus the CBC add-on |
Getting a reliable hemoglobin result
- Drink normally. Dehydration concentrates the blood and raises hemoglobin and hematocrit.
- Allow for altitude and smoking. Both raise hemoglobin (MedlinePlus), and MedlinePlus notes hematocrit rises for several weeks after moving to a higher altitude.
- Note where you are in your cycle. Heavy periods are a common cause of low hemoglobin; recording the timing helps explain a dip.
- Recheck on a schedule. After treatment for anemia starts, a repeat at 8 to 12 weeks shows whether it is working, and ferritin in the same draw shows whether stores are refilling.
At-home tests that include hemoglobin
Hemoglobin is on four SiPhox panels: Longevity Essentials, Heart & Metabolic, Ultimate 360 and GLP Optimization. SiPhox lists it as a capillary value measured by the HbA1c method, paired with a calculated hematocrit. It is not on Thyroid Focus or Hormone Focus. For a full count, SiPhox sells a CBC add-on at +$45 per test (EasyDraw only), which adds red cell count, white cell count, MCV, MCH, MCHC and RDW, or CBC and IGF-1 together for +$100.
| SiPhox panel | Biomarkers per test | Per test, with shipping | Listed as |
|---|---|---|---|
| Longevity Essentials | 31 | $149 | Hemoglobin (Blood) |
| Heart & Metabolic | 28 | $149 | Hemoglobin (Blood) |
| Ultimate 360 | 62 | $274 | Hemoglobin (Blood) |
| GLP Optimization | 46 | $224 | Hemoglobin (Blood) |
SiPhox is a wellness service with no doctor review included. A hemoglobin under the WHO cutoff should be confirmed with a venous CBC through your doctor. See our SiPhox review.
A note on home samples: SiPhox's partner lab tests capillary blood collected from the upper arm. SiPhox says its results show a 95% to 99% correlation with venous draws in its own quarterly comparisons against Labcorp and Quest, but it has not published a study of the EasyDraw device. If a result would change a treatment decision, confirm it with a venous test through your doctor.

Longevity Essentials
The default panel: heart, metabolic, hormone and inflammation markers in one draw.
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Heart & Metabolic
Lipids plus kidney and liver function: the panel for cardiovascular and metabolic risk.
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Ultimate 360
Everything on the four core panels plus iron studies, B12 and folate, GGT and PSA.
Check priceFrequently asked questions
What is a normal hemoglobin level?
13.8 to 17.2 g/dL for adult men and 12.1 to 15.1 g/dL for adult women, according to MedlinePlus. Labs vary slightly.
What hemoglobin level is anemia?
The WHO defines anemia as hemoglobin under 13.0 g/dL in men and under 12.0 g/dL in non-pregnant women, with lower cutoffs in pregnancy.
What causes high hemoglobin?
Dehydration, smoking, living at altitude, lung or heart disease, sleep apnea, testosterone therapy and polycythemia vera.
Is hemoglobin the same as HbA1c?
No. Hemoglobin measures oxygen-carrying protein; HbA1c measures the share of that hemoglobin with glucose attached. SiPhox measures both from the same sample.
Can I test hemoglobin at home?
Yes. SiPhox reports hemoglobin on Longevity Essentials, Heart & Metabolic, GLP Optimization and Ultimate 360, and sells a full CBC add-on for +$45.
Sources
- MedlinePlus Medical Encyclopedia: Hemoglobin
- MedlinePlus Lab Tests: Hemoglobin test
- MedlinePlus Medical Encyclopedia: Complete blood count
- World Health Organization: Guideline on haemoglobin cutoffs to define anaemia in individuals and populations (2024)
- Bhasin S et al. Testosterone therapy in men with hypogonadism: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab 2018
- SiPhox Health: panel comparison (checked 29 Sep 2026)
- SiPhox Health: Longevity Essentials panel, marker list and per-cycle add-ons
- SiPhox Health: Heart & Metabolic panel
- SiPhox Health: Ultimate 360 panel